Genomics Sevice

Short DNA sequence fragments are assembled into a complete genome sequence for species with an existing reference genome. For species without a reference genome, de novo assembly will be performed for DNA sequence fragments from Illumina, Nanopore, or PacBio sequencing.

Genome Annotation is annotating genes, coding regions, regulatory elements, and other functional components within the genome and annotating their functions to elucidate trait-related regulatory pathways.

Variant Detection is a type of analysis for identifying genomic variations, including single nucleotide polymorphisms (SNPs), insertions/deletions (Indels), and structural variations (e.g. copy number variations, inversions, and translocations). It studies how these variations lead to diseases or trait changes.

Comparative genomics involves comparing the genomes of different individuals or species to study their evolutionary relationships, gene function conservation, and variation patterns.

Population evolutionary studies involve using whole-genome resequencing to obtain genomic information from different subpopulations of a species. By comparing this data to a reference genome, researchers can identify highly accurate SNPs, Indels, structural variations (SVs), and copy number variations (CNVs). Based on this variation information, the genetic structure, gene flow, species formation mechanisms, and evolutionary dynamics of populations are explored, offering a molecular-level understanding of the species' evolutionary history.

GWAS combines population variation information with phenotypic trait data. Using linkage disequilibrium (LD) between genes (loci) as a basis, it statistically associates the diversity of target traits' phenotypes with the polymorphism of genes (loci). This method ultimately locates loci and genes associated with target traits, offering advantages such as wide material sources, extensive genetic variation, and comprehensive trait localization.